Tissue Oxygenation Imaging

The concept of Tissue Oxygenation Imaging aims to measure hypoxic tissue at the suborgan (millimeter) level. This is done to identify abnormalities like ischemia, injury, infections, cancer, and other medical conditions. Detecting these pathologic conditions is challenging with current technology, limiting early identification. Standard tools may also be invasive or restricted in form factor, hindering bedside or outpatient use.

Quantum sensors could enable more effective tissue oxygenation imaging. A possible mechanism involves a quantum-based instrument or spectrometer using tracers that bond to oxygen or reveal functional abnormalities. Sensors like optically pumped magnetometers (OPMs), nanodiamonds with nitrogen-vacancy (NV) centres, frequency comb breathalyzers, and gas detectors could be used. These would provide accurate oxygen level measurements of deep tissue through noninvasive procedures, with capabilities for medium- and long-term monitoring.

Implementing quantum tissue oxygenation imaging would allow for the detection of pathologic conditions far earlier than currently possible. The variety of form factors available for quantum sensors could enable imaging in bedside and outpatient settings. This technology would be useful for doctors across various specialisations, such as trauma, cardiology, and cancer, and potentially even in sports medicine clinics. It could lead to earlier diagnosis, lower medical costs, and collection of currently undetectable biomarker information